Polymorphonuclear leukocyte-induced vasocontraction and endothelial dysfunction. Role of selectins.

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Polymorphonuclear leukocyte-induced vasocontraction and endothelial dysfunction. Role of selectins.

The roles of selectin adhesion molecules (P- and L-selectin) and their counterreceptor sialyl Lewisx were investigated in polymorphonuclear leukocyte (PMN)-induced cat coronary vasocontraction and endothelial dysfunction. Unstimulated autologous PMNs (10(6) cells/mL) were added to organ chambers containing cat coronary artery rings stimulated with either thrombin (2 U/mL) or hydrogen peroxide (...

متن کامل

Influenza A virus-induced polymorphonuclear leukocyte dysfunction.

Previous studies have shown that influenza A virus can activate the polymorphonuclear leukocyte (PMN) respiratory burst and that upon subsequent stimulation of the cell there is depressed metabolic function. We examined the mechanism by which influenza virus causes PMN dysfunction by measuring the effect upon the chemiluminescent activity of cells of varying the type of influenza virus used, th...

متن کامل

Role of the Sialophorin (CD43) Receptor in Mediating Influenza A Virus- Induced Polymorphonuclear Leukocyte Dysfunction

Polymorphonuclear leukocytes (PMNLs) exposed to influenza A virus (IAV) undergo activation of the respiratory burst followed by depression of cell function when subsequently exposed to particulate or soluble stimuli. The effect of IAV on PMNLs is likely to be mediated through the attachment of IAV to one or more specific receptors. Recently, IAV has been shown to bind to the sialophorin protein...

متن کامل

Role of the sialophorin (CD43) receptor in mediating influenza A virus-induced polymorphonuclear leukocyte dysfunction.

Polymorphonuclear leukocytes (PMNLs) exposed to influenza A virus (IAV) undergo activation of the respiratory burst followed by depression of cell function when subsequently exposed to particulate or soluble stimuli. The effect of IAV on PMNLs is likely to be mediated through the attachment of IAV to one or more specific receptors. Recently, IAV has been shown to bind to the sialophorin protein...

متن کامل

Lysophosphatidylcholine in Oxidized Low-Densit Lipoprotein Increases Endothelial Susceptibility to Polymorphonuclear Leukocyte-Induced Endothelial Dysfunction in Porcine Coronary Arteries Role of Protein Kinase C

We have shown that transferred lysophosphatidylcholine (lysoPC) from oxidized low-density lipoprotein (OxLDL) to endothelial surface membrane activates protein kinase C (PKC) in endothelial cells, suggesting that Ox-LDL could alter endothelial functions through PKC activation. The purposes of the present study were to examine whether the endothelial susceptibility to polymorphonuclear leukocyte...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Arteriosclerosis and Thrombosis: A Journal of Vascular Biology

سال: 1994

ISSN: 1049-8834

DOI: 10.1161/01.atv.14.9.1509